You do not state your settings and therefore it is not possible to diagnose the reason, other than the obvious which is PTT is asserted when it should not be.
I suggest you refer to the User Manual Addendum (see MB1 section in Forum) and ensure you have ESDR2 PTT set per the instructions. If the problem persists it will be a settings error in DM780. Those settings will be dependent on your ESDR2 settings but if you follow the Addendum, you should use:
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