It would be cumbersome. In a contest you need ESM, enter sends message, and losing the contest screen focus to go to SDC just to send a macro that would be already on its way from the contest software is unrealistic. I maintain that the answer to the original question is found in the UMA.
For non-contest yes via TCI. I do not see how TCI is quicker than K9DUR, it is still a F key press, but TCI via SDC is better as it covers all modes and switches dynamically per the radio. In fact, in the next UMA edit, K9DUR will be removed as its had its day in the EE environment.